ABSTRACT
Objective To provide reference of the general physiological index, blood physiology and biochemistry for middle and old-aged cynomolgus monkey.Methods 119 cynomolgus monkey aged from 11~16 (80 were males and 39 were females) were involved in the study.We detected the general physiological index( body weight, the crown-rump length and waist circumference ) , hematology and blood biochemistry parameters respectively and compared these parameters between males and females.Results Between males and females, there were significant differences in Body weight, the crown-rump length and Waist circumference of the general physiological index(P 0.05).Conclusion It provides reference of general physiological index, blood physiology and biochemistry parameters of cynomolgus monkey and basis for their application in biomedical domain.
ABSTRACT
Objective: To compare the difference of maternal periodontal status and TNF-? levels in gingival cervical fluid in pregnancy with pre-term and full-term and find the relationship between periodontal infections and pre-term. Methods:The case group consisted of 28 women with pre-term and the control group consisted of 22 women giving birth in time. The clinical examination was performed before delivery. The periodontal conditions were evaluated on the basis of the following parameters: gingival index(GI), probing depths(PD), clinical attachment level(CAL) and sulcus bleeding index(SBI). Gingival crevicular fliud(GCF) samples were collected from all individuals and TNF-? levels were measured by enzyme-linked immunoabsorbent assay. Results:Clinical periodontal measures(GI, PD, CAL, SBI) in pre- term group were significantly greater than that in the control group. And pre- term group also showed higher prevalence of periodontitis. TNF-? in GCF was detected in 67.85% of pre-term group and in 27.27% of the control group. GCF volumes of case group significantly increased than that of control group. Significant negative correlations were observed between the gestational age at delivery and PD as well as GCF- volumes. Conclusion: There is a possible link between periodontal infections and pregnancy with pre-term condition.